Endocrine Abstracts

The hypothalamus plays a key role in the control of appetite and energy balance. The endogenous cannabinoids are widely distributed throughout the brain, including the hypothalamus, together with specific cannabinoid-1 (CB-1) receptors. Endogenous and exogenous cannabinoids induce hyperphagia, whereas the selective CB-1 receptor antagonist, SR 141716 (rimonabant), inhibits feeding and CB-1 knockout animals are leaner and eat less after an overnight fast. Ghrelin, the recently ...

Background: A possible association between severe acute respiratory syndrome coronavirus (SARS-CoV)-2 pandemic and subacute thyroiditis (SAT) has been reported.Objectives: To evaluate SAT clinical characteristics, correlating them to virus exposure and/or vaccine and to evaluate thyroid function according to the length of time after symptoms onset.Methods: We performed a prospective, observational, multi-centre study, considering t...